Topic: Specific Gene or protein causing impaired apoptosis in systemic lupus erythematosus pathogenesis
Pages: 21, Double spaced
Order type: Capstone Project
Language: English (U.S.)
Project Description / InstructionsThis would be a molecular biology capstone paper and PowerPoint presentation with speaker notes: it would have to include scientific figures and if needed statistics based off information from references. The topic should be a specific molecular mechanism causing impaired apoptosis leading to systemic lupus erythematosus.( (a gene or protein) and pathway) . It would be helpful to have the outlines and drafts in timely fashion that would be great. Here’s the rubric:1.
Requirements for the Human Disease Capstone Project:
a. Choose a well-focused topic centered on a molecular mechanism, gene (or group of genes), or pathway involved in a human disease that is approved by my faculty mentor by the 1st week of the semester. Topics should not have been reviewed and published in the last 3 years.
b. Write a scientific review article on the chosen topic. The review article should meet the following criteria:
i. Publication quality: format, grammar, spelling, and citations should be consistent with the published literature.
ii. 20-30 page (double-spaced, Times New Roman 12-point font with 1-inch margins) review with a 200-word (?) abstract, and introduction, and a minimum of 5 sub-headings. The Bibliography is not included in the page count, but any figures are.
iii. All pages should be numbered in the lower right-hand corner
iiii. Plagiarism of any form will not be tolerated and will result in a grade of “0” and dismissal from the program. Plagiarism includes failure to cite sources, even when appropriate paraphrasing is used, using direct quotes without quotation marks and citations, failure to cite figures used in
v. 15 minute presentation, with 5 minutes for questions your paper or presentation, or failure to paraphrase appropriately.
vi. A minimum of 30 references should be used and cited; at least 20 references (or 70%) of references must be from the last 5 years. ALL references cited in the main body must be primary articles, not review articles (though review articles may be cited in the introduction).
c. Prepare and present the capstone information in presentation form
i. The requirements of the presentation are:
2. Introduction: General disease information, why its important to study
3. Explanation of topic: rationale, and importance of addressing the topic
4. Explanation of molecular mechanism of the disease
5. Explanation of subtopics of paper
ii. Presentations should include appropriate use of images, with citations, and should not have excess text
iii. Grading criteria will include subject knowledge, clarity of the presentation, organization of the presentation, aesthetics of the PowerPoint, presentation skills, and response to questions.
2. Timeline: The following goals must be met at the times indicated if the student plans to graduate the same semester as he/she takes capstone. Failure to meet 2 or more of the deadlines at the times indicated will result in delaying the presentation and graduation until the following semester.
a. Week 1- Final topic approved and submitted (by email)
b. Feb3: Week 4- Complete outline with at least 15 references- include all subheadings: look at previous reviews to get ideas for what constitutes a subtopic
c. Mar3: Week 8- 1st complete rough draft
d. Mar 31: Week 12-2nd complete rough draft and presentation outline
e. April 14:Week 14- Final paper is due; complete draft of presentation
f. April 27/28:Week 16- Presentation/Symposium; paper revisions due (must highlight)
a. The capstone grade will be determined as follows:
i. Meeting Deadlines- 15%
ii. Final paper- 50%
iii. Presentation grade- 35%